Correlative light and electron microscopy /
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Imprint: | Amsterdam, Netherlands ; Boston, Mass. : Elsevier / Academic Press, ©2012. |
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Description: | 1 online resource (xix, 404 pages, [40] pages of plates) : illustrations (some color). |
Language: | English |
Series: | Methods in cell biology, 0091-679X ; v. 111 Methods in cell biology ; v. 111. |
Subject: | |
Format: | E-Resource Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11140148 |
Other authors / contributors: | Müller-Reichert, Thomas, 1962- Verkade, Paul. |
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ISBN: | 9780123914385 0123914388 9780124160262 0124160263 |
Notes: | Includes bibliographical references and index. |
Summary: | The combination of electron microscopy with transmitted light microscopy (termed correlative light and electron microscopy; CLEM has been employed for decades to generate molecular identification that can be visualized by a dark, electron-dense precipitate. This new volume of Methods in Cell Biology covers many areas of CLEM including a brief history and overview on CLEM methods, imaging of intermediate stages of meiotic spindle assembly in C. elegans embryos using CLEM, and capturing endocytic segregation events with HPF-CLEM. Covers many areas of CLEM by the best international scientists in the field. Includes a brief history and overview on CLEM methods. |
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