Cytotoxic drug resistance mechanisms /

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Bibliographic Details
Imprint:Totowa, N.J. : Humana Press, ©1999.
Description:1 online resource (xi, 238 pages) : illustrations
Language:English
Series:Methods in molecular medicine ; 28
Methods in molecular medicine ; 28.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11154662
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Other authors / contributors:Brown, Robert, 1956 January 8-
Böger-Brown, Uta.
ISBN:9781592596874
1592596878
9780896036031
0896036030
Notes:Includes bibliographical references and index.
Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010.
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212
digitized 2010 HathiTrust Digital Library committed to preserve
Print version record.
Summary:In Cytotoxic Drug Resistance Mechanisms, leading clinical and laboratory scientists describe cutting-edge methods for examining the mechanisms of cellular resistance to anticancer cytotoxics in human tumors. The protocols contain detailed instructions and extensive troubleshooting tips that allow researchers effectively to study a wide variety of drug resistance mechanisms, including aspects of drug-induced cell death, drug uptake/efflux, drug metabolism, and DNA repair. Each method is designed to help identify the correlation between molecular and biochemical data and the clinical responses of the patient. Cytotoxic Drug Resistance Mechanisms makes it possible to test established and laboratory-derived hypotheses with clinically derived tumor samples. State-of-the-art and readily reproducible, the methods presented here afford basic and clinical scientists a powerful complement of tools for investigating all the clinically relevant mechanisms used as markers of the biological response to anticancer chemotherapeutics today.
Other form:Print version: Cytotoxic drug resistance mechanisms. Totowa, N.J. : Humana Press, ©1999 0896036030
Standard no.:10.1385/1592596878