MIF : most interesting factor /

MIF : most interesting factor /

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Bibliographic Details
Imprint:	Singapore ; New Jersey : World Scientific, ©2007.
Description:	1 online resource
Language:	English
Subject:	Macrophage migration inhibitory factor. Macrophage migration inhibitory factor. Electronic books.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11168094

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Other authors / contributors:	Bucala, Richard.
ISBN:	9812775919 9789812775917
Notes:	Includes bibliographical references and index.
Summary:	In recent years, researchers have identified a pivotal, upstream role for macrophage migration inhibitory factor (MIF) in the innate immune response. This pioneering book describes this renaissance of knowledge in the biology of MIF. Topics covered include MIF's molecular mechanism of action, its counterregulatory action on the immunosuppressive properties of glucocorticoids, its role in the production of proinflammatory mediators as shown in cell-based and animal studies; and its central role in human inflammation. Human genetic studies have identified allelic forms of the MIF gene, and high-

Table of Contents:

Historical overview / R. David
MIF "rediscovered" / R. Bucala
Immunopathologic mechanisms relevant to diseases / H.Y. Lan
Structural studies of MIF / E. Lolis
MIF redox activity / J. Bernhgaen
MIF receptor-mediated signal transduction / C. Leng
MIF in innate immunity and infectious diseases / T. Calandra
MIF in parasitic and helminth infections / A.R. Satoskar
MIF in the pathogenesis of kidney disease / R.C. Atkins
MIF and CNS autoimmune disease / T.G. Forsthuber
MIF: wound repair / G.S. Ashcroft
MIF and atherosclerosis / C. Weber
Inflammatory arthritis / E. Morand
MIF alleles in infammatory arthritis / R. Donn
Adhesion-dependent signaling and growth control / R. Mitchell.