Translational animal models in drug discovery and development /

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Bibliographic Details
Imprint:	[Place of publication not identified] : Bentham Science Publishers, 2012.
Description:	1 online resource (viii, 275 pages)
Language:	English
Subject:	Animal models in research. Medicine -- Research. Animal models in research. Medicine -- Research. Electronic books.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11169431

Hidden Bibliographic Details
Other authors / contributors:	Wang, Xinkang.
ISBN:	9781608054695 1608054691 9781608055913
Notes:	Includes bibliographical references and index.
Summary:	Animal models of diseases play a pivotal role in drug discovery and development, not only for proof of the concept studies of efficacy, PK/PD relationship but also for drug safety assessment. Since considerable differences in variables exist between animal models and human models (such as genetics, physiology, anatomy, gene expression, heterogeneity of disease conditions, etc.), not all the preclinical models are able to represent the pathophysiological conditions in human diseases. Therefore, partly due to the lack of congruency between animal and human disease models, several proposed therap.
Other form:	Print version: Wang, Xinkang. Translational Animal Models in Drug Discovery and Development. Sharjah : Bentham Science Publishers, ©2012 9781608055913

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