Drug-DNA interaction protocols /

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Bibliographic Details
Imprint:Totowa, NJ : Humana Press, ©1997.
Description:1 online resource (x, 278 pages) : illustrations
Language:English
Series:Methods in molecular biology ; v. 90
Methods in molecular biology (Clifton, N.J.) ; v. 90.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11170746
Hidden Bibliographic Details
Other authors / contributors:Fox, Keith R.
ISBN:9781592595747
159259574X
1280837403
9781280837401
9786610837403
6610837406
089603447X
9780896034471
Notes:Includes bibliographical references and index.
Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010.
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212
English.
digitized 2010 HathiTrust Digital Library committed to preserve
Print version record.
Summary:In Drug-DNA Interactions, expert researchers describe powerful molecular techniques designed to illuminate and explore the interaction of drugs and ligands with DNA, often perfected in their own laboratories, . These easily reproducible methods involve sequence recognition properties, as well as physical approaches to measuring both the strength of interaction and the mode of drug binding to DNA. Drug interactions are also examined from a cellular perspective and for their usefulness in the development of new therapeutic agents. Drug-DNA Interactions will be highly useful to all investigators needing the kind of detailed experimental and technical information often omitted from scientific papers. Those wishing to expand their repertoire of experimental techniques or to improve their current techniques will also find these powerful methods particularly helpful in elucidating the action of existing therapeutic agents, as well as in designing new anticancer drugs with improved action and reduced toxicity.
Other form:Print version: Drug-DNA interaction protocols. Totowa, NJ : Humana Press, ©1997 089603447X
Standard no.:10.1385/089603447X.