Target identification and validation in drug discovery : methods and protocols /

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Bibliographic Details
Imprint:New York : Humana : Springer Science+Business Media, ©2013.
Description:1 online resource (xv, 371 pages) : illustrations (some color)
Language:English
Series:Methods in molecular biology, 1940-6029 ; v. 986
Methods in molecular biology (Clifton, N.J.) ; v. 986.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11173925
Hidden Bibliographic Details
Other authors / contributors:Moll, Jürgen.
Colombo, Riccardo.
ISBN:9781627033114
1627033114
9781627033107
1627033106
Digital file characteristics:text file PDF
Notes:Includes bibliographical references and index.
English.
Print version record.
Summary:The major reason for the elevated costs of drug development in the pharmaceutical industry is the high attrition rate. In Target Identification and Validation in Drug Discovery: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to identify and validate new target. These include methods and approaches covering biochemical, cell based, in vivo models and translational methods. Chapters also include selected case reports that demonstrate the integration of these technologies to real life experiences and to demonstrate the multiple use of more than one technology to increase knowledge on a specific target. These Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Target Identification and Validation in Drug Discovery: Methods and Protocols contains a comprehensive list of essential methods and clear protocols to follow.
Other form:Print version: Target Identification and Validation in Drug Discovery. Humana Pr Inc 2013 9781627033107
Standard no.:10.1007/978-1-62703-311-4