Transgenic mouse methods and protocols /

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Bibliographic Details
Edition:2nd ed.
Imprint:New York, N.Y. : Humana Press, ©2011.
Description:1 online resource (xi, 352 pages) : color illustrations
Language:English
Series:Methods in molecular biology ; v. 693
Methods in molecular biology (Clifton, N.J.) ; volume 693.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11233227
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Other authors / contributors:Hofker, Marten H. (Marten Harro)
Deursen, Jan van, 1930-
ISBN:9781607619741
1607619741
9781607619734
1607619733
9781607619758
160761975X
9781493956760
1493956760
Notes:Includes bibliographical references and index.
English.
Summary:The generation of genetically modified mice is absolutely crucial to gene function studies today, primarily because mice are genetically similar to man and because gene function studies in mice are in the context of a whole organism, making them particularly useful. In Transgenic Mouse Methods and Protocols, Second Edition, expert research explore current advances in the field through detailed laboratory protocols. Chapters provide a general introduction outlining how to deal with mice and how to generate transgenic mouse models, explore the generation of conditional and induced knockout and transgenic mice, and offer alternative routes to studying gene function in mice. Composed in the highly successful Methods in Molecular Biology"!series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Comprehensive and state-of-the-art, Transgenic Mouse Methods and Protocols, Second Edition is the ideal guide for all researchers interested in the latest information about the production and analysis of transgenic and knockout mice
Other form:Print version: Transgenic mouse methods and protocols. 2nd ed. New York, NY : Humana Press, ©2011
Standard no.:10.1007/978-1-60761-974-1.