The use of CRISPR/cas9, ZFNs, TALENs in generating site specific genome alterations /

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Bibliographic Details
Edition:First edition.
Imprint:Amsterdam : Elsevier/Academic Press, 2014.
©2014
Description:1 online resource (594 pages, 24 unnumbered pages of plates) : illustrations (some color).
Language:English
Series:Methods in enzymology, 0076-6879 ; volume 546
Methods in enzymology ; v. 546.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11239266
Hidden Bibliographic Details
Other authors / contributors:Doudna, Jennifer A., editor.
Sontheimer, Erik J., editor.
Anders, Carolin, contributor.
ISBN:9780128013342
0128013346
9780128016152
0128016159
9780128011850
9780128014158
0128014156
Digital file characteristics:text file
Notes:Includes bibliographical references at the end of each chapter and indexes.
English.
Print version record.
Summary:This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers recent research and methods development for changing the DNA sequence within the genomes of cells and organisms. Focusing on enzymes that generate double-strand breaks in DNA, the chapters describe use of molecular tools to introduce or delete genetic information at specific sites in the genomes of animal, plant and bacterial cells.
Other form:Print version: Use of CRISPR/cas9, ZFNs, TALENs in generating site specific genome alterations. First edition. San Diego, California : Academic Press, ©2014 xx, 549 pages Methods in enzymology ; Volume 546 0076-6879 9780128011850