Translating molecular biomarkers into clinical assays : techniques and applications /

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Bibliographic Details
Imprint:Cham : Springer, 2016.
Description:1 online resource (215 pages)
Language:English
Series:AAPS Advances in the Pharmaceutical Sciences Series ; v. 37
AAPS advances in the pharmaceutical sciences series ; v. 37.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11265837
Hidden Bibliographic Details
Other authors / contributors:Weiner, Russell.
Kelley, Marian.
ISBN:9783319407937
3319407937
9783319407920
3319407929
Digital file characteristics:data file
Notes:Biospecimen Research.
Print version record.
Summary:This handbook covers established and advanced techniques for biomarker analysis, such as guidelines and strategies for assay validation methods; different mathematical models that are necessary in contemporary drug discovery and development; and evaluation of new cytometry methods. Expertly curated by two practicing professionals in drug development and biotherapeutics, individual chapters are selected for novel and sound research; information is chosen based on its relevance to lab applications and clinical trials, such as the topic of selecting animal models for their relevancy to humans. The book is multifaceted, discussing the ethics and issues with biospecimens and providing an in-depth analysis to the differences between pre-clinical and clinical assay development. The book is an essential read for general readers who need an introduction to the history and background of biomarkers, and it also provides critical analyses of various new validation methods for practitioners and researchers.
Other form:Print version: Weiner, Russell. Translating Molecular Biomarkers into Clinical Assays : Techniques and Applications. Cham : Springer International Publishing, ©2016 9783319407920
Standard no.:10.1007/978-3-319-40793-7

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