Personalized pathway-activated systems imaging in oncology : principal and instrumentation /

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Bibliographic Details
Imprint:Singapore : Springer, 2017.
Description:1 online resource
Language:English
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11272113
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Other authors / contributors:Inoue, Tomio (Of Yokohama Shiritsu Daigaku), editor.
Yang, David J., editor.
Huang, Gang (Of Shanghai jiao tong da xue), editor.
ISBN:9789811033490
9811033498
9789811033483
981103348X
Digital file characteristics:text file PDF
Notes:Includes bibliographical references at the end of each chapters.
Online resource; title from PDF title page (SpringerLink, viewed March 8, 2017).
Summary:This comprehensive volume covers radiopharmaceuticals developed for pathway-directed systems in imaging and theranostic applications. We now are at the cutting edge of providing personalized treatment with increased use in oncology of these new radiopharmaceuticals. Trends in high-resolution instrumentation development, quality assurance systems and regulatory compliance for radiopharmaceuticals, clinical evaluation of radiopharmaceuticals, and benefits and pitfalls of the current clinical FDG PET are discussed. Radiopharmaceuticals are used for diagnosis of diseases of the central nervous and cardiovascular systems and for staging, restaging, and treatment planning for cancers. Nuclear biomarkers allow precise measurement of molecular pathways on a whole-body image upon administration of functional radiolabeled agents, and nuclear imaging agents have potential use in patient selection, pharmacokinetic, dosage-finding, and proof-of-concept studies. Nuclear imaging agents and hybrid instrumentation also provide sensitive and specific answers for differential responsiveness in therapeutic outcome. This book serves as a reference for moving the discovery and development of radiopharmaceuticals from the workbench to clinical applications. It thus benefits not only clinicians but also translational research scientistsℓ́ℓmolecular biologists, chemists, imaging scientists, pharmaceutical developers, physicists, and support staff.
Other form:Print version: Personalized pathway-activated systems imaging in oncology. Singapore : Springer, 2017 981103348X 9789811033483
Standard no.:10.1007/978-981-10-3349-0