TRAIL, Fas Ligand, TNF and TLR3 in cancer /

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Bibliographic Details
Imprint:Cham : Springer, 2017.
Description:1 online resource
Language:English
Series:Resistance to targeted anti-cancer therapeutics ; v. 12
Resistance to targeted anti-cancer therapeutics ; v. 12.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11322902
Hidden Bibliographic Details
Other authors / contributors:Micheau, Olivier, editor.
ISBN:9783319568058
3319568051
9783319568065
331956806X
9783319860060
3319860062
9783319568041
3319568043
Digital file characteristics:text file
PDF
Notes:Includes bibliographical references and index.
Online resource; title from PDF title page (EBSCO, viewed July 31, 2017).
Summary:This volume provides the current understanding of death receptor's/TLR3 signaling regulation in cancer. Death receptors, including TRAIL-R1, TRAIL-R2, Fas and TNF-RI, owing to their ability to trigger apoptosis and to contribute to the elimination of cancer cells by the immune system have been considered, to variable extent, as important therapeutic targets for cancer therapy. But an increasing body of evidence suggests that some of these receptors may also contribute to tumorigenesis, or that new players such as TLR3 may be targeted for cancer therapy due to their ability to behave like death receptors.
Other form:Printed edition: 9783319568041
Standard no.:10.1007/978-3-319-56805-8