Hidden Bibliographic Details
Other authors / contributors: | Micheau, Olivier, editor.
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ISBN: | 9783319568058 3319568051 9783319568065 331956806X 9783319860060 3319860062 9783319568041 3319568043
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Digital file characteristics: | text file PDF
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Notes: | Includes bibliographical references and index. Online resource; title from PDF title page (EBSCO, viewed July 31, 2017).
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Summary: | This volume provides the current understanding of death receptor's/TLR3 signaling regulation in cancer. Death receptors, including TRAIL-R1, TRAIL-R2, Fas and TNF-RI, owing to their ability to trigger apoptosis and to contribute to the elimination of cancer cells by the immune system have been considered, to variable extent, as important therapeutic targets for cancer therapy. But an increasing body of evidence suggests that some of these receptors may also contribute to tumorigenesis, or that new players such as TLR3 may be targeted for cancer therapy due to their ability to behave like death receptors.
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Other form: | Printed edition: 9783319568041
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Standard no.: | 10.1007/978-3-319-56805-8
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