Mitochondrial DNA and diseases /

Mitochondrial DNA and diseases /

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Bibliographic Details
Imprint:Singapore : Springer, 2017.
Description:1 online resource (233 pages)
Language:English
Series:Advances in Experimental Medicine and Biology ; v. 1038
Advances in experimental medicine and biology ; v. 1038.
Subject:
Mitochondrial DNA.
Mitochondrial DNA -- Abnormalities.
Mitochondrial Diseases.
DNA, Mitochondrial.
Mitochondria.
Mitochondrial DNA.
Mitochondrial DNA -- Abnormalities.
Electronic book
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11389333
Hidden Bibliographic Details
Other authors / contributors:Sun, Hongzhi.
Wang, Xiangdong (Professor of clinical bioinformatics)
ISBN:9789811066740
9811066744
9789811066733
9811066736
Digital file characteristics:text file PDF
Notes:Includes bibliographical references.
Print version record.
Summary:The book describes molecular principles and mechanisms by which mitochondrial DNA (mtDNA) can drive the occurrence of diseases and the latest understanding of mtDNA biology. The book explores roles of mtDNA mutation and genetic changes in cancer, with a special focus on lung cancer, and the significance of approach, application, and bioethics of mtDNA sequencing. Authors made a great effort to overview roles of mtDNA signaling pathways, base excision repair, methylation, USP30-mediated regulation, mitochondrial ribosome, autophagy pathways, or ROS-dependent signaling in the pathogenesis, diagnosis, prevention and treatment of diseases. It also demonstrates the importance of basic mitochondrial genetics and the relationship between mutations and disease phenotypes and ageing. This book covers not only the basic information of mtDNA, the relationship of mtDNA and disease, but also mtDNA in stem cell and mitochondria and metabolism etc. The book is written for biological and clinical students and researchers in the field of mtDNA-associated diseases.
Other form:Print version: Sun, Hongzhi. Mitochondrial DNA and Diseases. Singapore : Springer Singapore Pte. Limited, ©2017 9789811066733
Standard no.:10.1007/978-981-10-6674-0

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