Acute promyelocytic leukemia : a clinical guide /

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Bibliographic Details
Imprint:Cham, Switzerland : Springer, [2018]
Description:1 online resource
Language:English
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11654527
Hidden Bibliographic Details
Other authors / contributors:Abla, Oussama, editor.
Lo Coco, Francesco, editor.
Sanz, Miguel A., editor.
ISBN:9783319642574
331964257X
9783319642567
3319642561
9783319642567
Digital file characteristics:PDF
text file
Notes:Includes bibliographical references and index.
Online resource; title from PDF title page (EBSCO, viewed May 02, 2018).
Summary:This book provides a comprehensive overview on the clinical issues and biology of acute promyelocytic leukemia (APL) and on the molecular mechanisms of targeted therapy with ATRA and ATO. The text covers major topics such as the pathophysiology of APL coagulopathy, biologic and clinical differences between children and adults with APL, and the role of minimal residual disease monitoring. Additionally, the book summarizes historical, current, and future treatment strategies in both adults and children, while highlighting the most recent therapeutic recommendations for relapsed disease and the evolving indications for autologous and allogeneic stem cell transplant. This volume also features chapters focusing on secondary APL and therapy, late effects, rare presentations such as APL in the elderly and during pregnancy, and rare APL variants that may represent therapeutic challenges. Written by top experts in the field, Acute Promyelocytic Leukemia: A Clinical Guide is a valuable resource for clinicians and researchers who treat and investigate this disease in children and adults.
Other form:Printed edition: 9783319642567
Standard no.:10.1007/978-3-319-64257-4