Understanding the host immune response against Mycobacterium tuberculosis infection /

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Bibliographic Details
Imprint:Cham : Springer, 2018.
Description:1 online resource
Language:English
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11706575
Hidden Bibliographic Details
Other authors / contributors:Venketaraman, Vishwanath, editor.
ISBN:9783319973678
3319973673
9783319973685
3319973681
9783030073442
3030073440
9783319973661
3319973665
Digital file characteristics:text file PDF
Notes:Online resource; title from PDF title page (EBSCO, viewed October 2, 2018).
Summary:According to the World Health Organization, approximately one third of the world's population is latently infected with Mycobacterium tuberculosis (M. tb [LTBI]), of whom about 9 million have active tuberculosis (TB). It is estimated that approximately 2 million individuals die each year from active TB. An estimated 14.4% of these individuals have HIV and M. tb co-infection. TB has long been known to be one of the leading causes of death in HIV-infected individuals. Recent evidence now indicates that individuals with type 2 diabetes, the elderly, and chronic smokers are also increasingly susceptible to TB infection, the ability of their immune system to fight off active TB infection having been compromised by their condition. This book therefore aims to provide a detailed review of recent advances in the research that involves characterizing the host's immune responses against TB infection in conditions such as HIV, diabetes, chronic cigarette smoking and aging, and strategies to restore favorable immune responses against this deadly pathogen.
Other form:Printed edition: 9783319973661
Printed edition: 9783319973685
Standard no.:10.1007/978-3-319-97367-8
10.1007/978-3-319-97