Hidden Bibliographic Details
| Other authors / contributors: | Silvestri, Guido (Professor of pathology and laboratory medicine), editor.
Lichterfeld, Mathias, editor.
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| ISBN: | 9783030028169
303002816X
9783030028176
3030028178
9783030028152
3030028151
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| Digital file characteristics: | text file PDF
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| Notes: | Online resource; title from PDF title page (SpringerLink, viewed October 18, 2018).
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| Summary: | This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.
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| Other form: | Print version: HIV-1 latency. Cham, Switzerland : Springer, [2018] 3030028151 9783030028152
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| Standard no.: | 10.1007/978-3-030-02816-9
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