HIV-1 latency /
Imprint: | Cham, Switzerland : Springer, [2018] |
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Description: | 1 online resource |
Language: | English |
Series: | Current topics in microbiology and immunology, 0070-217X ; volume 417 Current topics in microbiology and immunology ; 417. |
Subject: | |
Format: | E-Resource Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11718264 |
Summary: | This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public. |
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Physical Description: | 1 online resource |
ISBN: | 9783030028169 303002816X 9783030028176 3030028178 9783030028152 3030028151 |
ISSN: | 0070-217X ; |