Synthesis of therapeutic oligonucleotides /

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Bibliographic Details
Imprint:Singapore : Springer, 2018.
Description:1 online resource
Language:English
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11761271
Hidden Bibliographic Details
Other authors / contributors:Obika, Satoshi, editor.
Sekine, Mitsuo, editor.
ISBN:9789811319129
981131912X
9789811319112
9811319111
Digital file characteristics:text file PDF
Notes:Includes bibliographical references.
Online resource; title from PDF title page (EBSCO, viewed December 11, 2018)
Summary:This book presents the latest knowledge on a broad range of topics relating to the synthesis of natural and artificial oligonucleotides with therapeutic potential. Nucleic acid-based therapeutics are attracting much attention, and numerous therapeutic oligonucleotides, such as antisense oligonucleotides, siRNAs, splice-switching oligonucleotides, and nucleic acid aptamers, are being evaluated in clinical trials for the treatment of a variety of diseases. Synthesis of Therapeutic Oligonucleotides covers a broad range of topics in the field that are of high relevance to researchers, including the synthesis of natural and chemically modified oligonucleotides, the development of novel nucleic acid analogs, industrial scale synthesis and purification of oligonucleotides, and important aspects of chemistry, manufacturing, and controls (CMC). The aim is to provide new insights and inspire fresh ideas in nucleic acid chemistry that may ultimately lead to novel concepts and techniques and the discovery of more effective nucleic acid drugs. The book will be of high value for both established researchers in the field and students intending to specialize in nucleic acid chemistry research.
Other form:Print version: Synthesis of therapeutic oligonucleotides. Singapore : Springer, 2018 9811319111 9789811319112
Standard no.:10.1007/978-981-13-1912-9