Biomarkers in cancer therapy : liquid biopsy comes of age /

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Bibliographic Details
Imprint:Singapore : Springer, [2019]
Description:1 online resource
Language:English
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11895823
Hidden Bibliographic Details
Other authors / contributors:Shimada, Hideaki, editor.
ISBN:9789811372957
9811372950
9789811372940
Digital file characteristics:text file PDF
Notes:Includes bibliographical references.
Online resource; title from PDF title page (EBSCO, viewed June 4, 2019).
Summary:This book sheds new light on research into liquid biopsy biomarkers for cancer screening. The chapters in the first half address exosomes, circulating cell-free DNA and autoantibodies, and main solid cancers, along with companion biomarkers - all of which serve as the basis for exploring key research questions for future clinical trials in the book's second half. The study of biomarkers has evolved rapidly thanks to advances in precision medicine. While conventional cancer biomarker research is focused on proteomics or gene analysis of resected tissue, diagnostic markers have since become significant in terms of gauging the effectiveness of molecularly targeted drugs or the likelihood of a favorable prognosis. In addition, conventional treatment strategy, which draws on archives of resected tissue samples, is now gradually being replaced by monitoring with the use of liquid biopsy, which is poised to become the new mainstream in molecular targeting therapy. The contributing authors discuss in detail biomarkers, molecular targets for treatment, monitoring markers to evaluate treatment responses, prognostic markers, and screening and early diagnosis. Accordingly, this excellent collection of texts will benefit not only oncologists, but also medical and biological researchers and pharmaceutical scientists involved in the latest cancer research.
Other form:Printed edition: 9789811372940
Printed edition: 9789811372964
Printed edition: 9789811372971
Standard no.:10.1007/978-981-13-7295-7