Hidden Bibliographic Details
| Other authors / contributors: | Tettelin, HerveĢ.
Medini, Duccio.
|
|---|
| ISBN: | 9783030382810
3030382818
9783030382827
3030382826
9783030382834
3030382834
303038280X
9783030382803
|
|---|
| Digital file characteristics: | text file
PDF
|
|---|
| Notes: | Includes bibliographical references.
Open access.
|
|---|
| Summary: | This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The books respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.
|
|---|
| Other form: | Print version: Pan-genome. Cham : Springer, 2020 303038280X 9783030382803
|
|---|
| Standard no.: | 10.1007/978-3-030-38281-0
10.1007/978-3-030-38
|
|---|
