Hidden Bibliographic Details
| Other authors / contributors: | Kumar, Dhruv.
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| ISBN: | 9789811519918
9811519919
9789811519901
9811519900
9789811519925
9811519927
9789811519932
9811519935
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| Digital file characteristics: | text file PDF
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| Notes: | Includes bibliographical references.
Print version record.
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| Summary: | This book illustrates various aspects of cancer cell metabolism, including metabolic regulation in solid tumours vs. non-solid tumours, the molecular pathways involved in its metabolism, and the role of the tumour microenvironment in the regulation of cancer cell metabolism. It summarizes the complexity of cancer cell metabolism in terms of the switch from anaerobic to aerobic glycolysis and how mitochondrial damage promotes aerobic glycolysis in cancer cells. The respective chapters provide the latest information on the metabolic remodelling of cancer cells and elucidate the important role of the signalling pathways in reprogramming of cancer cell metabolism. In addition, the book highlights the role of autophagy in cancer cell metabolism, and how metabolic crosstalk between cancer cells and cancer-associated fibroblasts promotes cancer cell progression. In closing, it summarizes recent advancements in drug development through targeting cancer metabolism.
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| Other form: | Print version: Kumar, Dhruv. Cancer Cell Metabolism: a Potential Target for Cancer Therapy. Singapore : Springer, ©2020 9789811519901
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| Standard no.: | 10.1007/978-981-15-1991-8
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