Neurodevelopmental disorders : employing iPSC technologies to define and treat childhood brain diseases /

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Bibliographic Details
Imprint:Cham : Springer, 2020.
Description:1 online resource (307 p.).
Language:English
Series:Advances in Neurobiology ; v.25
Advances in neurobiology ; 25.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/12606134
Hidden Bibliographic Details
Other authors / contributors:DiCicco-Bloom, Emanuel.
Millonig, James H.
ISBN:9783030454937
3030454932
9783030454920
Notes:Description based upon print version of record.
6 Regulation of 15Q11-Q13 Gene Expression and Therapeutic Strategies
Summary:This book contains a compendium of induced pluripotent stem cells (iPSCs) articles and reviews concerning state of the art technologies and how they are being applied to human neurodevelopmental disorders. With the establishment of effective technologies to produce iPSCs and their derivatives, like neural precursors, neurons, and glia, researchers have new platforms to study neurodevelopmental disorders. iPSC technology enables researchers to study how human neurons develop in individuals with neurodevelopmental disorders, providing an unparalleled opportunity to investigate their etiology. In turn, researchers have now begun to understand the underlying molecular and cellular pathways that contribute to human diseases. iPSCs technologies also provide an emerging tool for future translational studies and disease classification. The chapters will emphasize how among the diverse idiopathic and genetic disorders, there are common clinical as well as cellular and molecular phenotypes.
Other form:Print version: DiCicco-Bloom, Emanuel Neurodevelopmental Disorders : Employing IPSC Technologies to Define and Treat Childhood Brain Diseases Cham : Springer International Publishing AG,c2020 9783030454920
Standard no.:10.1007/978-3-030-45