Hidden Bibliographic Details
Other authors / contributors: | Wu, Baojian, editor.
Lu, Danyi, editor.
Dong, Dong, editor.
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ISBN: | 9789811588075 9811588074 9811588066 9789811588068
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Digital file characteristics: | text file PDF
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Notes: | Description based upon print version of record. Includes bibliographical references.
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Summary: | This book summarizes the recent advances for the understanding of circadian clock system in the regulation of drug metabolism and pharmacokinetics. Basic knowledge in the field of circadian clock and pharmacokinetics are systemically introduced to make it easier for readers to understand the entire book's contents. The rhythmic expression of DMEs (drug-metabolizing enzymes) and transporters are summarized, and the underlying mechanisms thereof (i.e., regulation by circadian oscillators) are discussed. Typically, evidence for the DME- and transporter-mediated chronopharmacokinetics, chronotoxicity and chronoefficacy are highlighted in this book.
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Other form: | Print version: Wu, Baojian Circadian Pharmacokinetics Singapore : Springer Singapore Pte. Limited,c2020 9789811588068
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Standard no.: | 10.1007/978-981-15-8807-5
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