G Protein-Coupled Receptors in Health and Disease. Part B /

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Bibliographic Details
Imprint:Amsterdam ; Boston : Elsevier/Academic Press, 2009.
Description:1 online resource (xii, 173 pages, 4 unnumbered pages of plates) : illustrations (some color).
Language:English
Series:Progress in molecular biology and translational science, 1877-1173 ; v. 89
Progress in molecular biology and translational science ; v. 89.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/12616311
Hidden Bibliographic Details
Other authors / contributors:Tao, Ya-Xiong, editor.
ISBN:9780123747563
0123747562
1283608588
9781283608589
9786613921031
6613921033
0080911943
9780080911946
Notes:Includes bibliographical references and index.
Text in English.
Summary:G protein-coupled receptors (GPCRs) transduce signals from a diverse array of endogenous ligands, including ions, amino acids, nucleotides, lipids, peptides, and large glycoprotein hormones. They are also responsible for our sensing of exogenous stimuli, including photons and odorants. GPCRs regulate almost every aspect of our physiological functions. It is estimated that 40% to 50% of currently used therapeutic drugs target GPCRs directly or indirectly. Because the current drugs target only a small portion of the GPCRs, opportunities for targeting the remaining GPCRs is enormous. This volume reviews the latest developments in this rapidly advancing field. * This series provides a forum for discussion of new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields.
Other form:0-12-374756-2