Mapping genetic interactions /

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Bibliographic Details
Imprint:	New York, NY : Humana Press, [2021]
Description:	1 online resource (1 PDF file (xv, 361 pages)) : illustrations.
Language:	English
Series:	Methods in molecular biology, 1940-6029 ; 2381 Springer protocols Methods in molecular biology (Clifton, N.J.) ; v. 2381. Springer protocols (Series)
Subject:	Gene mapping -- Laboratory manuals. Chromosome Mapping Gene Order Gene mapping Laboratory Manual Laboratory manuals Laboratory manuals.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/12660407

Hidden Bibliographic Details
Other authors / contributors:	Vizeacoumar, Franco, editor. Freywald, Andrew, editor.
ISBN:	9781071617403 1071617400 9781071617397
Notes:	Includes bibliographical references and index. Description based online resource; title from PDF title page (SpringerLink, viewed October 5, 2021).
Summary:	This volume details methods of identifying synthetic lethal, genetic interactions by various approaches in different model systems including human cancer cells. Chapters guide readers through genetic interactions in model organisms, RNA interference, CRISPR/Cas9 based genome editing technologies, drug-gene interactions, mapping chemical genetic interactions, synergistic drug-gene relations, single cell sequencing, gene expression profiling, and novel genetic interactions. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Genetic Interaction Mapping aims to be a useful practical guide to researches to help further their study in this field.
Standard no.:	10.1007/978-1-0716-1740-3

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