IPCS mode of action framework /

Saved in:
Bibliographic Details
Corporate author / creator:International Program on Chemical Safety.
Imprint:Geneva, Switzerland : World Health Organization, c2007.
Description:iv, 123 p. : ill. ; 30 cm.
Language:English
Series:Harmonization Project document ; no. 4
Subject:
Format: E-Resource Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/7478766
Hidden Bibliographic Details
ISBN:9789241563499 (pbk.)
9241563494 (pbk.)
Notes:Cover title.
"IPCS International Programme on Chemical Safety."
"This project was conducted within the IPCS project on the Harmonization of Approaches to the Assessment of Risk from Exposure to Chemicals"--P. [i].
"Published under the joint sponsorship of the World Health Organization, the International Labour Organization and the United Nations Environment Programme, and produced within the framework of the Inter-Oganization Programme for the Sound Management of Chemicals"--P. [i].
Includes bibliographical references.
Also available online.
Summary:The use of structured frameworks in chemical risk assessment promotes transparent, harmonized approaches. This publication presents two IPCS frameworks originally published in Critical Reviews in Toxicology. Part 1 contains the IPCS Framework for Analyzing the Relevance of a Cancer Mode of Action for Humans, along with three case studies illustrating its application. Part 2 contains the IPCS Framework for Analyzing the Relevance of a Non-Cancer Mode of Action for Humans. The frameworks provide a means of ensuring a transparent evaluation of the data, identification of key data gaps and of information that would be of value in the further risk assessment of the chemical in question.--Publisher's description.