Death receptors in cancer therapy /

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Bibliographic Details
Imprint:	Totowa, N.J. : Humana Press, c2005.
Description:	1 online resource (xi, 374 p.) : ill.
Language:	English
Series:	Cancer drug discovery and development Cancer drug discovery and development.
Subject:	Apoptosis. Cell receptors. Cancer -- Molecular aspects. Cellular signal transduction. Neoplasms -- immunology. Neoplasms -- therapy. Cell Death -- immunology. Gene Therapy -- methods. Receptors, Tumor Necrosis Factor. Apoptosis. Cancer -- Molecular aspects. Cell receptors. Cellular signal transduction.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/8877369

Hidden Bibliographic Details
Other authors / contributors:	El-Deiry, Wafik S.
ISBN:	9781592598519 159259851X 1588291723 (alk. paper) 9781588291721 (alk. paper)
Notes:	Includes bibliographical references and index. Description based on print version record.
Summary:	This is an in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. The topics of particular interest include resistance to apoptosis, TRAIL signaling, death receptors in embryonic development, mechanisms of caspase activation, and death receptor mutations in cancer. Additional chapters address death.
Other form:	Print version: Death receptors in cancer therapy. Totowa, N.J. : Humana Press, c2005 1588291723 9781588291721

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