Oncogenes meet metabolism : from deregulated genes to a broader understanding of tumour physiology /

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Bibliographic Details
Imprint:Berlin ; New York : Springer, c2008.
Description:1 online resource (xv, 264 p.) : ill.
Language:English
Series:Ernst Schering Foundation symposium proceedings, 0947-6075 ; 2007-4
Ernst Schering Foundation Symposium Proceedings ; 2007/4.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/8887308
Hidden Bibliographic Details
Other authors / contributors:Kroemer, Guido.
ISBN:9783540794776 (hbk. : alk. paper)
3540794778 (hbk. : alk. paper)
9783540794783 (electronic bk.)
3540794786 (electronic bk.)
9786611862497
6611862498
Notes:Includes bibliographical references.
Summary:In 1920s, Otto Warburg described the phenomenon of a aerobic glycolysisa (TM), the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburga (TM)s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed for most human tumours. With the advent of molecular biology the focus in tumour research has shifted towards the search for oncogenes. However, the interest in cancer molecular profiling eventually led to a renaissance of the Warburg effect trying to combine genetic alterations with effe.
Other form:Print version: Oncogenes meet metabolism. Berlin ; New York : Springer, c2008 9783540794776 3540794778