Oncogenes meet metabolism : from deregulated genes to a broader understanding of tumour physiology /
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| Imprint: | Berlin ; New York : Springer, c2008. |
|---|---|
| Description: | 1 online resource (xv, 264 p.) : ill. |
| Language: | English |
| Series: | Ernst Schering Foundation symposium proceedings, 0947-6075 ; 2007-4 Ernst Schering Foundation Symposium Proceedings ; 2007/4. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/8887308 |
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| 245 | 0 | 0 | |a Oncogenes meet metabolism : |b from deregulated genes to a broader understanding of tumour physiology / |c G. Kroemer ... [et al.], editors. |
| 260 | |a Berlin ; |a New York : |b Springer, |c c2008. | ||
| 300 | |a 1 online resource (xv, 264 p.) : |b ill. | ||
| 336 | |a text |b txt |2 rdacontent |0 http://id.loc.gov/vocabulary/contentTypes/txt | ||
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| 490 | 1 | |a Ernst Schering Foundation symposium proceedings, |x 0947-6075 ; |v 2007-4 | |
| 504 | |a Includes bibliographical references. | ||
| 505 | 0 | |a Mitochondria and Cancer; Role of the Metabolic Stress Responses of Apoptosis and Autophagy in Tumor Suppression; The Interplay Between MYC and HIF in the Warburg Effect; Using Metabolomics to Monitor Anticancer Drugs; Biomarker Discovery for Drug Development and Translational Medicine Using Metabonomics; Pyruvate Kinase Type M2: A Key Regulator Within the Tumour Metabolome and a Tool for Metabolic Profiling of Tumours; Molecular Imaging of Tumor Metabolism and Apoptosis; Minimally Invasive Biomarkers for Therapy Monitoring; Use of Metabolic Pathway Flux Information in Anticancer Drug Design. | |
| 520 | |a In 1920s, Otto Warburg described the phenomenon of a aerobic glycolysisa (TM), the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburga (TM)s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed for most human tumours. With the advent of molecular biology the focus in tumour research has shifted towards the search for oncogenes. However, the interest in cancer molecular profiling eventually led to a renaissance of the Warburg effect trying to combine genetic alterations with effe. | ||
| 650 | 0 | |a Oncogenes. |0 http://id.loc.gov/authorities/subjects/sh85094721 | |
| 650 | 0 | |a Cancer |x Pathophysiology. |0 http://id.loc.gov/authorities/subjects/sh87005720 | |
| 650 | 0 | |a Cell metabolism. |0 http://id.loc.gov/authorities/subjects/sh85021656 | |
| 650 | 1 | 2 | |a Oncogenes. |
| 650 | 2 | 2 | |a Neoplasms |x genetics. |
| 650 | 2 | 2 | |a Neoplasms |x metabolism. |
| 650 | 7 | |a HEALTH & FITNESS |x Diseases |x Cancer. |2 bisacsh | |
| 655 | 4 | |a Electronic books. | |
| 650 | 7 | |a Cancer |x Pathophysiology. |2 fast |0 http://id.worldcat.org/fast/fst00845410 | |
| 650 | 7 | |a Cell metabolism. |2 fast |0 http://id.worldcat.org/fast/fst00850203 | |
| 650 | 7 | |a Oncogenes. |2 fast |0 http://id.worldcat.org/fast/fst01045729 | |
| 700 | 1 | |a Kroemer, Guido. |0 http://id.loc.gov/authorities/names/n94801434 |1 http://viaf.org/viaf/92175128 | |
| 776 | 0 | 8 | |i Print version: |t Oncogenes meet metabolism. |d Berlin ; New York : Springer, c2008 |z 9783540794776 |z 3540794778 |w (DLC) 2008925641 |w (OCoLC)293319991 |
| 830 | 0 | |a Ernst Schering Foundation Symposium Proceedings ; |v 2007/4. | |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/978-3-540-79478-3 |y SpringerLink |
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| 928 | |t Library of Congress classification |a RC268.42 O55 2008 |l Online |c UC-FullText |u http://dx.doi.org/10.1007/978-3-540-79478-3 |z SpringerLink |g ebooks |i 11466148 | ||