Stimulation of trigeminal afferents improves motor recovery after facial nerve injury : functional, electrophysiological and morphological proofs /

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Bibliographic Details
Imprint:	Berlin ; New York : Springer, 2013.
Description:	1 online resource (122 p.)
Language:	English
Series:	Advances in Anatomy, Embryology and Cell Biology ; 213 Advances in Anatomy, Embryology and Cell Biology ; 213.
Subject:	Facial Nerve -- surgery. Facial nerve -- Surgery. Facial nerve -- Surgery.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/9849291

Hidden Bibliographic Details
Other authors / contributors:	Skouras, Emmanouil.
ISBN:	9783642333118 (electronic bk.) 3642333117 (electronic bk.) 9783642333101
Notes:	Includes bibliographical references and index. Description based upon print version of record.
Summary:	Recovery of mimic function after facial nerve transection is poor: the successful regrowth of axotomized motoneurons to their targets is compromised by (i) poor axonal navigation and excessive collateral branching, (ii) abnormal exchange of nerve impulses between adjacent regrowing axons and (iii) insufficient synaptic input to facial motoneurons. As a result, axotomized motoneurons get hyperexcitable and unable to discharge. Since improvement of growth cone navigation and reduction of the ephaptic cross-talk between axons turn out be very difficult, the authors concentrated on the third detrimental component and proposed that an intensification of the trigeminal input to axotomized electrophysiologically silent facial motoneurons might improve specificity of reinnervation.
Other form:	Print version: 9783642333101

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