Drug design : methodology, concepts, and mode-of-action /

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Bibliographic Details
Author / Creator:Klebe, Gerhard.
Uniform title:Wirkstoffdesign. English
Imprint:Berlin : Springer 2013.
Description:1 online resource (720 pages) : color illustrations
Language:English
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/9852328
Hidden Bibliographic Details
ISBN:9783642179075 (electronic bk.)
364217907X (electronic bk.)
9783642179068
Notes:Description based on print version record.
Summary:Unique work on structure-based drug design, covering multiple aspects of drug discovery and development. Fully colored, many images, computer animations of 3D structures (these only in electronic form). Makes the spatial aspects of interacting molecules clear to the reader, covers multiple applications and methods in drug design. Structures by mode of action, no therapeutic areas. Of high relevance for academia and industrial research. Focus on gene technology in drug design, omics-technologies computational methods experimental techniques of structure determinationmultiple examples on mode of action of current drugs, ADME-tox properties in drug development, QSAR methods, combinatorial chemistry, biologicals, ribosome, targeting protein-protein interfaces.
Other form:Print version: Klebe, Gerhard. Drug design 3642179061
Standard no.:10.1007/978-3-642-17907-5